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Comparative studies of natural groups of organisms

           (c) They change their shapes depending  Life cycle of Plasmodium sp.
               on the host it inhabits. For instance,  The parasite  in the form of sporozoites
               plasmodium  is sickle shaped in        enters the blood stream of the human
               salivary glands of mosquito, while it is   being after a mosquito bite. It then travels
               amoeboid in liver cells of human.      to the liver and invades it (Figure 3.15).

                                                      The sporozoites grow, divide and produce
          FOR ONLINE READING ONLY
           Structure of Plasmodium sp.                many haploid forms called merozoites or
           The  Plasmodium  is oval shaped, and  schizozoites in liver cells. The merozoites
           lacks contractile vacuoles and locomotory  in the liver cells exit and re-enter blood
           organs. The apical end is a bridged cone- stream, where red blood cells are invaded.
           shaped projection demarcated by the polar  The merozoites multiply in the red blood
           rings. A single mitochondrion is generally   cells by asexual reproduction. In the red
           present at the posterior end and the Golgi   blood cells,  they develop  into  schizonts
           apparatus is unremarkable.  Just beneath   (feeding  stage),  which rupture  the  cells,
           the inner membrane, there is a row of      releasing newly formed merozoites which
           microtubules,  which originate from the    then invade other red blood cells. Some
                                                      of the merozoites in infected blood cells,
           polar end of the apical end and continue to   leave  a cycle  of asexual  replication.
           the posterior end. Attached to the nucleus,   Instead of replicating,  the merozoites
           there  is an endoplasmic  reticulum,  a    in  these  cells  develop  into  sexual  forms
           network of membranous tubules within       of the parasite called  male and female
           the cytoplasm (Figure 3.14). Additionally,   gametocytes.  The cycle in mosquito
           there are  rhoptries,  which are the       starts when the mosquito bites an infected
           specialised secretory organelles.          human and ingests gametocytes. The male
                                                      and female gametes fuse to form diploid
                                                      zygote,  which  develops  into  moving
                              Golgi apparatus         ookinete.  The ookinete  burrows in the
                               Nucleus                midgut wall of mosquito, forming oocyst
                                                      on the  other side.  Growth and division
                               Endoplasmic reticulum
                                                      of each oocyst produce numerous active
                               Mitochondrion          haploid forms called  sporozoites. After

                                                      8 to 15 days (depending on the species),
                               Rhoptries              the oocyst bursts, releasing  sporozoites
                                                      into  the  body cavity  of the  mosquito,
                              Microtubules            from where they travel  to, and invade
                                                      the  mosquito  salivary  glands.  The  cycle
                                                      of human infection re-starts when the

             Figure 3.14:  Structure of a Plasmodium sp.   mosquito taking a blood meal injects the
                                                      sporozoites from its salivary glands into
                                                      the human blood stream.




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