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Biology for Advanced Level Secondary Schools

                                                      (d) Gives knowledge about the process and
                                                         significance of cellular differentiation,
                                                         that is, a process in which cells are
                                                         specialised  for their functions, such
                                     Chambers of
                                     the cork cell       as reproductive cells, absorptive cells,
                                                         and nerve cells.
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                                                      (e) Enables us to understand how similar
                                                         cells are organised into tissues.
           Figure 1.1:  First view of the cork cells by Robert  (f)  Helps to show how organisms are
                             Hooke                       evolutionarily  related. For example,
           Source: http://ucmp.berkeley.edu              in the biochemical  evolution  theory
                                                         of origin of life on the earth, various
           He was later followed by  Anton von           chemical  compounds were combined
           Leeuwenhoek, who in 1674 discovered free      and mobilised into prokaryotes, which

           living cells in pond water. Leeuwenhoek       gave rise to eukaryotes in the course of
           made a microscope consisting of a single      evolution.
           high-quality lens which could magnify an  (g) Helps to understand  the  basis of
           object 270 times. This instrument was at that   genetics; the location,  structure,
           time referred to as a compound microscope.    chemistry, and role of nucleic  acids,
           With this microscope, Leeuwenhoek was         Deoxyribonucleic  acid (DNA)  and
                                                         Riboxyribonucleic acid (RNA).
           able to make a number of  important        (h) Cytopathology, a study of cellular
           scientific discoveries, including single-     abnormalities,  helps  to  diagnose
           celled animals, plants, bacteria, and         diseases through observation  of
           spermatozoa.                                  cellular changes.


           The importance of studying cytology        1.2  The Cell theory
           The  study of cytology  helps  us to
           understand the role of cells  as the       The origin of the concept of “Cell theory”
           building blocks of all living organisms,   can be traced to as far back as 1830s
           including their anatomy and physiology.    when two scientists,  Matthias  Schleiden
           Additionally, the significance of studying   a Belgian  botanist  (1838) and  Theodor
           cytology include the following:            Schwann, a German  zoologist  (1839)
           (a) Helps to realise the role of cells  provided  the  first  definition  of  the  cell.
               in metabolic  processes such as  They stated that, all living organisms,
               respiration, protein synthesis, excretion,   both simple and complex, are made up of
               and growth.                            one or more cells. They described a cell as
           (b) Aids in understanding  the detailed    the structural and functional unit of life.
               structure and functions of different
               cells and organelles.                  This led to formulation of the Cell theory.
           (c) Enhances an understanding  on the      The Cell  theory states that  “All living
               structural (anatomical  and chemical)   organisms are made up of cells”. In 1855,
               composition of cells.                  Rudolf Virchow, a German physiologist,

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