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Biology for Advanced Level Secondary Schools

           Pepsinogen: It is produced by the chief  type is the large intestine, which among
           cells of the stomach wall. It is a precursor  other functions, is mainly important in re-
           or  inactive  form  of  pepsin.  Pepsinogen  absorption of water from the food residues
           is activated  by hydrochloric  acid  in the   before they are egested.
           stomach  to  form  pepsin;  an  enzyme
           responsible  for the  breaking  down of    The small intestine
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           polypeptides into peptides.                This part of the intestine has smaller
                                                      diameter  compared  to  that  of  the  large
           Prorennin: This is a precursor of rennin,   intestine and for this reason it is called a
           the enzyme that catalyses the conversion
           of soluble milk protein into an insoluble   small intestine. The diameter of the small
           milk protein.  In other words, rennin is   intestine of human being is approximately
           an important enzyme in coagulation  or     2.5 cm while the large intestine has a
           curdling of milk in the stomach.  The      diameter of about 7.6 cm, which is about
           coagulated milk is semi solid and it can   three times wider than the small intestine.
           be retained in the stomach for a relatively   The small intestine  is the longest of all
           long time for proper digestion. This is very   parts  of the  alimentary  canal.  It  has the
           important in lactating young mammals.      length of about 9 metres in a living person.
           In the stomach, mechanical digestion also   The small intestine  muscles are tight in
           occurs due to continuous contractions      the living body which makes it slightly
           of the stomach wall, which enhances        shorter, unlike in a dead person where it
           breaking down  of food mechanically.       becomes somewhat longer (about twice as
           The combined action of mechanical and      much longer as its normal size in a living
           chemical  digestion produces a creamy      person). This is because death makes the
           paste,  an  acid  chyme.  The  formation  of   small intestine to lose its muscle tone and
           this chyme stimulates the receptors on the   stretches as it becomes loose. Unlike the
           stomach wall, which in turn stimulates     large intestine, the small intestine  has
           the pyloric sphincter muscles to relax and   numerous  folds  and  projections  called
           allow food to pass into the duodenum.      villi on its lining, which are important in
           Digestion of food in the stomach may take   increasing  the  surface area for digestion
           on average about 2 to 4 hours.             and absorption of food. The surface area
                                                      of the small intestine of a human is about
                                                             2
           The intestines                             200 m which is surprisingly closer to
           The intestines  are contained within the   100 times the surface area of our body
           abdominal  part  of the  body and  they    skin. Schematically, the small intestine is
           constitute the longest and massive part of   normally surrounded by the large intestine
           the alimentary canal. The word intestine   in three sides.
           comes from a Latin  word  intestinum,
           meaning 'gut or internal'. The intestines are   The small intestine is not straight rather
           of two types, namely the small intestine   a coiled  tube, which literally  has three
           which forms a vital part in the digestion   major distinct regions, namely duodenum,
           and absorption of foods.  The second       jejunum,  and ileum.  The sectioning  of
                                                      the small intestine is based on its internal

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