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Biology for Advanced Level Secondary Schools

           namely  glycolysis,  Kreb’s cycle,  and  Carbohydrates
           oxidative phosphorylation. Respiration is  These are the main respiratory substrates
           an important process as it yields chemical  used by most respiring cells. Carbohydrates
           energy in the form of ATP, which enables  include polysaccharides, disaccharides, and
           organisms to perform life activities,  monosaccharides.  Polysaccharides, such
           such as movement,  growth, excretion  as glycogen, cellulose, and starch must be
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           and reproduction.  Respiration  process  hydrolysed into simple monosaccharides,
           involves oxidation of organic compounds  such as glucose; in contrast, disaccharides
           known as respiratory substrates. These are  have  to undergo hydrolysis into  three
           carbohydrates, fats, or proteins.          monosaccharides, namely glucose, galactose,
                                                      and fructose, depending on the type of the
           6.3.1 Respiratory substrates and their     disaccharide  that has been hydrolysed.
           energy value                               Monosaccharides are usually in the form
           Different respiratory substrates release   of hexose sugars. After their production, they
           different  amounts of energy (Table        are then utilised in the respiratory pathways
           6.2).  The difference  in energy values    to release energy.
           of respiratory  substrates  is  due  to  the   Lipids (fats and oils)
           amount of hydrogen atoms present in each   Lipids can be used as a respiratory substrate
           substrate. The more hydrogen atom in the   when the carbohydrates are exhausted. When
           molecule  of a respiratory substrate,  the   hydrolysed, each molecule releases three
           more  energy (ATP) is generated  during    fatty acids and one glycerol molecule. Fatty
           respiration.   Mitochondria    synthesise  acid are energy-rich compounds that enter
           water using the hydrogen atoms from        the respiratory pathways in order to release
           organic  molecules, such as glucose, and   energy.
           the  oxygen atoms  they  take  in as they
           respire. So, the more the hydrogen bonds   Protein
           are broken, the larger the amount of  Generally, protein is not used as an energy
           energy released.  Lipids’  energy  density  source unless the body has no other option.
           is more than twice that of carbohydrates  When all carbohydrate and lipid reserves
           because of their long fatty acid tails with  are fully utilised, proteins come into use.
           large number of hydrogen atoms.            Proteins  are  not  used  in  the  first  place
                                                      because of the variety of vital roles they
           Table 6.2: Respiratory substrates and their energy  play in the body. Proteins are hydrolysed

           values                                     into amino  acids and then  deaminated.
            S/N Respiratory       Energy value        Deamination involves the removal of the
                  substrate       (KJ/g)              amino  group.  The  remaining acid  may
                                                      enter the  Kreb’s cycle directly  or may
            1     Carbohydrates        15.8           be converted into fatty acids before they
            2     Lipids               39.4           enter  the  Kreb’s cycle.  The  amount  of

            3     Protein              17.0           ATP produced from protein metabolism is
                                                      slightly less than glucose metabolism for
                                                      equivalent weights.


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