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Biology for Secondary Schools


           Effects                                    damage to the hypothalamus or pituitary
           Uncontrolled diabetes can lead to severe   gland, and nephrogenic diabetes insipidus,
           complications affecting multiple organ     which results from the kidneys’ failure to
           systems. Chronic hyperglycemia damages     respond to ADH.
           blood vessels, increasing the risk of stroke,
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           heart disease, and hypertension. Diabetic   Causes
           neuropathy causes pain, numbness, or       There are several causes which include head
           tingling in the extremities, while diabetic   injuries, brain tumors, genetic mutations,
           retinopathy may lead to blindness. Kidney   kidney disease, and certain medications
           damage (diabetic nephropathy) can result   like lithium.
           in kidney failure (chronic kidney disease),
           requiring  dialysis  or  transplantation.   Symptoms
           Additionally, poorly managed diabetes  The main symptoms of diabetes insipidus
           weakens the immune system, making  include excessive urination (polyuria),
           infections more frequent and severe.       extreme thirst (polydipsia), dehydration,
           Prevention and management                  and nocturia (frequent urination at night).
           Preventing diabetes mellitus, particularly  Individuals may produce up to 20 liters
           Type 2 diabetes, involves maintaining  of dilute urine per day, leading to severe
           a healthy lifestyle. A balanced diet rich  dehydration if fluid intake is not sufficient.
           in fiber, whole grains, lean proteins,  Other symptoms include dry skin,
           and healthy fats helps regulate blood  fatigue, muscle weakness, and electrolyte
           sugar levels. Regular physical activity  imbalances.
           improves insulin sensitivity and promotes  Effects
           weight management. Avoiding excessive  If left untreated, diabetes insipidus can
           consumption of sugary foods, tobacco,  lead to severe dehydration, which may
           managing stress and refined carbohydrates  cause confusion, dizziness, low blood
           reduces the risk of insulin resistance.  pressure, and shock. Chronic dehydration
           Routine blood sugar monitoring and regular  can result in kidney damage and increased
           check-ups can help detect and manage  risk of urinary tract infections. Electrolyte
           prediabetes before it develops into full-  imbalances can cause muscle cramps,
           blown diabetes.                            irregular heart rhythms, and neurological
                                                      disturbances.
           Diabetes inspidus
           This is a rare disorder caused by a deficiency   Prevention and management
           of antidiuretic hormone (ADH) or the       While diabetes insipidus caused by genetic
           kidneys’ inability to respond to ADH. ADH,   factors cannot be prevented, maintaining
           also known as vasopressin, helps regulate   proper hydration and monitoring medication
           the  body’s  fluid  balance. The  primary   side effects can help manage symptoms.
           types of diabetes insipidus include central   Avoiding head injuries, managing kidney
           diabetes insipidus, which occurs due to



                                                   126               Student’s Book - Form Three



     BIOLOGY FORM 3 FINAL EDITED 16.09.2025.indd   126                                    23/10/2025   11:52:49                     KAMISHNA
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