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Excretion



           The process of urine formation             reabsorption (selective reabsorption) and
                       Activity 4.3:                  secretion or removal of materials.

            Demonstrating the process of urine        Glomerular filtration(ultrafiltration)
            formation                                 This is the first step in the formation of urine
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            Materials                                 from the blood. Ultrafiltration occurs in the
            Nephrone model, funnel, filter paper,     glomerulus (plural: glomeruli). The lumen of
                beaker, coloured water                the afferent arteriole is significantly smaller

            Procedure                                 than the efferent arteriole. As a result, a
            1.  Place a filter paper inside a Bowman’s   very high hydrostatic pressure is set in the
                capsule of the nephrone model.        glomerulus when blood passes through
                                                      it. This pressure forces plasma through
            2.  Pour colored water into the funnel    the capillary walls in the glomerulus. The
                and observe how it filters into the   plasma contains water, glucose, amino
                beaker.                               acids, urea, salts, uric acid, vitamins,

            3.  Compare the liquid obtained in a      hormones, white blood cells, blood platelets
                beaker with the poured liquid in the   and plasma. Red blood cells and proteins
                bowman’s capsule.                     are retained in the blood capillaries because
                                                      the cells and proteins are too large to pass
            Safety precaution
                                                      through the wall. This process is called
            (a) Ensure the beaker is properly placed   ultrafiltration and the fluid which passes
                to avoid water spillage.              into Bowman’s capsule is known as the
            (b) All safety gears should be properly   glomerular filtrate. The glomerular filtrate
                used.                                 collects in the capsule and enters the renal
            Questions                                 tubule at the proximal convoluted tubule
            1.  How do nephrone structures facilitate   which is coiled to increase the surface area
                their functions?                      for reabsorption of substances.
            2.  Why is selective reabsorption         Reabsorption (selective reabsorption)
                necessary for body homeostasis?       As  glomerular filtrate moves  along

                                                      the tubules, most of the substances are
           The blood from afferent arteriole which    reabsorbed back into the blood. When the
           enters Bowman’s capsule is rich in glucose,   blood passes in proximal convoluted tubule,
           fatty acids, amino acids, vitamins, proteins,   glucose, amino acids and some amount of
           urea and excess salts. The formation of    water are reabsorbed. As filtrate moves to
           urine from blood involves three steps,     the descending limb of loop of Henle, most
           which all occur in the nephrones of the    of the salts are reabsorbed then the filtrate
           kidneys as shown in Figure 4.4. The steps   moves to the distal convoluted tubule
           are glomerular filtration (ultrafiltration),   where more salts and water are reabsorbed.





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                                                                                          23/10/2025   11:52:44
     BIOLOGY FORM 3 FINAL EDITED 16.09.2025.indd   89
     BIOLOGY FORM 3 FINAL EDITED 16.09.2025.indd   89 KAMISHNA                            23/10/2025   11:52:44









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