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Biology for Advanced Level Secondary Schools


           Glycoprotein (a branch of
           carbohydrate attached to protein)                    Glycolipid (a branch of carbohydrate
               Peripheral                                       attached to lipid)
               protein                                          Phospholipid head
                                                                               Phospholipid  layer
                                                                Phospholipid tail
               Phospholipid
               bilayer                                         Cholesterol
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                                                       Channel protein with pore
                                                       Protein on one side of the membrane

                                                        Trasmembrane protein

                        Figure 1.7: Structure of a plasma membrane as per Fluid Mosaic Model


           Lipids and lipid-soluble  substances are  Functions of the plasma membrane
           allowed to cross the hydrophobic region  (a) It covers the surface of every living cell
           while non-lipids are not allowed  to          and acts as a barrier which separates
           cross. Large molecules, such as glucose,      the cytoplasm from extracellular
           fatty  acids,  glycerol  and  amino  acids    environment.
           are repelled by the hydrophobic region     (b) It allows passage of some materials
           and  therefore,  they  diffuse through        in and out of the  cells  (selective
           special  transport  proteins  called  channel   permeability).
           proteins and carrier proteins by facilitated   (c) It facilitates the transmission of nerve
           diffusion.
                                                         impulse in the nervous system.
           The  strength  of  the  model  is  that,  it   (d) It functions as a receptor site for
           realises the presence of the phospholipid     hormonal  and neural  transmission  of
           bilayer and protein layer. It also realises   chemical stimuli.
           the  presence  of pores in  the  membrane   (e) It  aids cell-to-cell  recognition  when
           and the presence of cholesterol  in the       membranes of two cells come together.
           membrane.  The model  explains  the        (f)  It serves as a base for attachment of
           presence  of polar  head  (hydrophilic)       the  cytoskeleton in some organisms
           and non-polar (hydrophobic) tail  in          and as the cell wall in others. Thus, the
           phospholipids.  Furthermore,  the  model      cell  membrane supports the cell  and
           explains the presence of glycolipid,  as      maintains its shape.
           receptors that allow the cell to respond
           to chemical  messengers which regulate     Adaptations of the cell surface
           the activities of the cell. It is true that the   membrane
           membrane is a dynamic (ever-changing its   The cell  membrane  is specialised  to its
           structure) with phospholipids in constant   functions as follows:
           motion. The weakness of the model is that   (a) Presence of glycolipids, glycoproteins
           it does not indicate or explain the presence   and phospholipids for detection of
           of electrolytes in the plasmalemma.           stimuli, such as antigens and antibodies.


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