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Cytology

           ribosomes  bound to  it  at  any  one  time  reticulum once a specific protein-nucleic
           are  not a stable  part  of this organelle’s  acid  complex  forms in the  cytosol. This
           structure,  as they  are  constantly  being  special  complex  forms when a  free
           bound and released from the membrane.  ribosome begins to translate the mRNA.
           A ribosome only binds to the endoplasmic
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                                          Ribosomes                              Cisternae













                                              Cisternae





                          (a)                                        (b)
                          Figure 1.10: The structure of endoplasmic reticulum (a) RER (b) SER

           Functions of rough endoplasmic             endoplasmic reticula are generally found in
           reticulum                                  adipose cells, interstitial cells, and glycogen
           The rough endoplasmic reticulum has the    storing cells of the liver. They also occur in
           following functions:                       conduction fibres of the heart, spermatocytes
           (a) They are sites for protein synthesis, due   and leucocytes. The muscle cells are also
               to the presence of ribosomes.
           (b) They provide pathways for transportation   rich in smooth endoplasmic reticulum known
                                                      as the sarcoplasmic reticulum.
               of materials through the cell, such as
               proteins synthesised on the ribosomes.  Functions of smooth endoplasmic
           (c) They provide a large surface area for   reticulum
               chemical reactions to take place.      (a)  It is essential for synthesis, secretion,
                                                         and storage of lipids, carbohydrate and
           Smooth endoplasmic reticulum (SER)            other non- protein products.
           This type of endoplasmic reticulum possesses   (b)  It  contains  enzymes  that  breakdown
           smooth walls, because the ribosomes are not   chemical substances in liver cells.
           attached to its membranes (Figure 1.10b).  (c)  It  plays a  fundamental  role  in  the
           The smooth endoplasmic reticulum occurs       synthesis of steroids, which later form
                                                         hormones.
           mostly in those cells which are involved in   (d)  It stores calcium ions in its lumen and
           metabolism of  glycogen and lipids, such as   releases them into the cytoplasm when
           phospholipids and cholesterol. The smooth     needed.


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