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Biology for Advanced Level Secondary Schools

           fusion of the outer and inner membranes  Functions of the nucleus
           of the envelope.  The nucleus contains  (a) It controls  all  metabolic  activities  of
           chromatin,  consisting of  DNA, which is      the cell.
           bounded by basic proteins called histones.  (b) It contains hereditary  information  of
           During nuclear division, chromatin            the cell, hence, it transmits genetic
           stains  more  intensely  and becomes          information to daughter cell.
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           more conspicuous because  it  condenses  (c) It takes part in the  formation  of
           into  more tightly  coiled  threads called    ribosomes and RNA, thus it controls
           chromosomes. However, some remains            protein synthesis.
           tightly coiled and continue to stain intensely  (d) It controls cell division when required
           and this is called heterochromatin.  It is    as DNA replication is essential for cell
           seen as a dark patch,  usually occurring      division.
           near the nuclear envelope. The remaining
           loosely coiled chromatin is euchromatin.     Exercise 1.5
           It contains DNA that is genetically active
           during interphase.                           1.  Describe the structure of the
                                                           nucleus of a cell.
           The nucleolus                                2.  Explain the role of nucleolus.
           The nucleolus  is a cellular  structure
           present  in the nucleus  of a eukaryotic     3.  Why is the nucleus said to be the
           cell. The nucleolus appears as a rounded        controller of all cellular activities?
           and darkly stained  structure inside  the
           nucleus. It contains nucleolar  organisers  Endoplasmic reticulum
           that synthesise ribosomes by transcribing  The endoplasmic reticulum is a network
           and assembling ribosomal  RNA (Figure  of flattened membranes bound sacs called
           1.9).  The nucleoli vary in number from  cisternae.  Some  of the  endoplasmic

           one to many nucleoli within a single cell   reticula  are encrusted with ribosomes
           nucleus of a plant or an animal cell.      and termed Rough Endoplasmic Reticula
                                                      (RER), while those without ribosomes are
                 Ribosomes                            known as Smooth Endoplasmic Reticula
            Rough endoplasmic                         (SER).  The quantity of both rough and
            reticulum                                 smooth endoplasmic reticula in a cell
              Nucleolus                               can slowly interchange  from one type
                                                      to  the  other, depending  on the  changing
             Chromatin
                                                      metabolic activities of the cell.
           Nucleoplasm

           Nuclear pore                               Rough endoplasmic reticulum (RER)
                                                      The surface of the rough endoplasmic
               Nuclear
               envelope                               reticulum contains protein-manufacturing
                                                      ribosomes, giving  it  a “rough”  structure
                  Figure 1.9: Structure of a nucleus  or surface (Figure 1.10a). However, the

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