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Gas exchange and respiration

           Importance of the Kreb’s cycle             proton and electron  acceptor are known
           Kreb’s cycle  is an  economical  way of  as anaerobes.  In anaerobes, other less-
           turning food components in the cell into  oxidising  substances  such  as  sulphate
                                                                                   -
           usable energy. Only the acetyl groups are  ion  (SO ), nitrate  ion (NO ), sulphur,
                                                               2-
                                                              4
                                                                                  3
           destroyed in the cycle. The seven enzymes  and fumarate are used.  These terminal
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           that carry out the various reactions and the   electron acceptors have smaller reduction
           intermediate  compounds on which these     potentials  than  oxygen.  This  means
           enzymes act can be used again and again.   that  less energy is released  per  oxidised
                                                      molecule. Generally, anaerobic respiration
                                                      is less efficient in energy production than
           Moreover, many of the intermediate
           compounds produced in the Kreb’s cycle     aerobic respiration. It is mainly used by
                                                      prokaryotes that live in environment
           are of value as starting materials for the   devoid of oxygen. Many anaerobic
           synthesis of amino acids, carbohydrates,   organisms are obligate anaerobes as they
           and other cellular products. Pyruvates are   can only respire anaerobically  and they
           broken down to carbon dioxide. Thus, the   die in the presence of oxygen. Muscles

           Kreb’s cycle  degrades  macromolecules     do also respire anaerobically  whenever
           into simpler molecules. The Kreb’s cycle   there  is  deficiency  or  lack  of  oxygen  at
           releases  ATP,  NADH  and  FADH. The  a particular  tissue point.  This creates
           ATP is directly  utilised  by the  cellular  the  basis for categorising  anaerobic
           activities while the NADH and FADH are  respiration  into  alcoholic  fermentation
           metabolites for oxidative phosphorylation  and lactic acid fermentation.
           of the electron transport system in which
           ATP are produced.                          Alcoholic fermentation
                                                      Alcoholic  fermentation  is also  called
           The fate of pyruvic acid under             ethanol  fermentation,  which  occurs  in
           anaerobic condition                        cells, such as plant and yeast cells (Figure
             Task 6.7                                 6.11).  This  biological  process converts
             Carry out library and internet search    two pyruvates into two acetaldehydes
             to  find  out  if  the  bacteria  and  yeast   producing  two carbondioxide  molecules
             can form alcohols in the absence of      as a waste product. The two acetaldehydes
             oxygen or they possess  a metabolic      are then converted  into two ethanol
             pathway that does not involve oxygen.    molecules  by using hydrogen ions from
             Write down your findings.
                                                      NADH;  converting  NADH  back into
                                                           +
                                                      NAD . Ethanol  fermentation  has many
           In the absence  of oxygen, the  principal
           product of glycolysis (pyruvate) enters    uses, including  producing  alcoholic
           a  fermentation  process.  The organisms   beverages, ethanol fuel, as well as raising
           that  do  not  use  oxygen  as  the  final   reagent in baking bread.



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