Page 104 - Biology_Form_3
P. 104

Excretion



           persistent consumption of food rich in     Jaundice is a medical condition in which
           purine. Red meat is an example of high     the skin, sclera and mucous membranes
           purine food. Medication such as diuretics   turn yellowish because of high level of
           also increases the risk of gout because they   bilirubin. Bilirubin is a bile pigment.
           stimulate and raise the level of uric acid in   Besides liver cirrhosis, jaundice may be
          FOR ONLINE READING ONLY
           the body. Overweight also increases the risk   also caused by hepatitis, gallstones and
           of developing gout.                        tumours. Symptoms of jaundice includes
                                                      yellowing of the skin, gastrointestinal
           Effects of gout include the formation of   bleeding, abdominal swelling, weight loss
           kidney stones. This means that uric acid   and fatigue.
           crystals are collected in the urinary system
           and develop into kidney stones. Recurrent   (i) Polycystic kidney disease (PKD)
           gout  causes  damage  to  the  joints. The   Polycystic kidney disease (PKD) is a
           kidneys also can be damaged by uric acid   genetic disorder characterized by the
           buildup, which may lead to kidney stone    development of numerous fluid-filled cysts
           formation.                                 in the kidneys, leading to enlarged kidneys
                                                      and impaired function. There are two main
           Maintaining high fluid intake, avoiding
           excess alcohol and maintaining a healthy   types: Autosomal dominant PKD (ADPKD),
           body weight are some preventive measures   which typically manifests in adulthood, and
           against gout. Individuals with gout can also   autosomal recessive PKD (ARPKD), a more
           reduce symptoms by taking balanced diet    severe form that appears in infancy or early
           regularly.                                 childhood. Symptoms of PKD include high
                                                      blood pressure, abdominal or lower back

           (h) Liver cirrhosis                        pain, blood in the urine, frequent kidney
                                                      infections, kidney stones, and progressive
           This is a condition in which liver cells   loss of kidney function, potentially leading
           degenerate and fibrous tissue is formed    to kidney failure. Preventive measures
           leading to scarring and liver failure. It   involve regular blood pressure monitoring,
           may be caused by many factors including    maintaining a low-sodium diet, staying
           alcohol intake, worms infestation in the   hydrated, avoiding smoking, and engaging
           liver, hepatitis or obstruction of the gall   in regular physical activity. Treatment
           bladder. Symptoms includes headache,       includes blood pressure management using
           nausea, vomiting, lack of appetite and     ACE inhibitors or angiotensin II receptor
           weight loss. The person with this disorder   blockers, pain management through
           should be given fat free food and stop     prescribed medications, and antibiotics for
           taking alcohol. The person is also advised to   urinary tract infections. Recent advances
           undergo medical treatment on gall bladder   include Tolvaptan, a vasopressin receptor
           stones and worm infestation or hepatitis if   antagonist that has been shown to slow
           they are found to be the cause. Later stages   the progression of kidney function
           of liver cirrhosis may lead to jaundice.   decline in ADPKD patients. Additionally,




                                                   97



                                                                                          23/10/2025   11:52:45
     BIOLOGY FORM 3 FINAL EDITED 16.09.2025.indd   97
     BIOLOGY FORM 3 FINAL EDITED 16.09.2025.indd   97 KAMISHNA                            23/10/2025   11:52:45









 KAMISHNA
   99   100   101   102   103   104   105   106   107   108   109