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Biology for Secondary Schools


           gene therapy using clustered regularly  an increased risk of blood clots. Preventive
           interspaced palindromic repeats (CRISPR)  measures include maintaining a low-sodium
           is being explored to correct PKD mutations,  diet to reduce fluid retention, consuming a
           offering potential future treatments.      high-protein diet to compensate for protein
                                                      loss, avoiding nephrotoxic medications, and
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           (j) Interstitial cystitis (bladder pain  undergoing regular kidney function tests.
           syndrome)
           Interstitial Cystitis (IC), also known as               Exercise 4.5
           bladder pain syndrome (BPS), is a chronic
           condition characterized by inflammation of   1.  A patient experiences swollen feet,
           the bladder wall, leading to persistent pelvic   fatigue, and blood in the urine.
           pain and urinary discomfort. The exact cause    Based on your knowledge of
           is unknown, but possible factors include        excretory system disorders, identify
           defects in the bladder lining, autoimmune       the possible condition and suggest
           responses, allergies, infections, and genetic   control measures.
           predisposition. Symptoms of IC include      2.  A person frequently experiences
           chronic pelvic pain, frequent urination         severe pain while urinating and
           (often in small amounts), urgency to            notices cloudy urine with a foul
           urinate, pain during sexual intercourse, and    smell.  What disorder might the
           pressure or discomfort in the bladder region.   person have, and what preventive
           Preventive measures focus on identifying        measures should be taken?
           and avoiding personal dietary triggers      3.  Compare kidney stones and urinary
           such as caffeine, alcohol, and spicy foods,     tract infections in terms of causes,
           practicing  stress-reduction  techniques,       symptoms, and control measures.
           engaging in bladder training exercises, and     Present your findings in a table.
           maintaining a healthy lifestyle.
                                                       4.  Explain how kidney failure affects
           (k) Nephrotic syndrome                         homeostasis in the body. Suggest
           Nephrotic syndrome is a kidney disorder        three possible interventions to
           caused by damage to the glomeruli, the         manage the condition.
           filtering units of the kidneys, leading to
           excessive protein loss in the urine. The             Chapter Summary
           primary causes include autoimmune
           diseases (such as lupus), diabetes mellitus,   1.  Excretion is the biological process
           infections, and certain medications that        of removing metabolic waste
           affect kidney function. Symptoms include        products from the body to maintain
           severe swelling (oedema), particularly in       homeostasis. Living organisms
           the legs, ankles, and face, foamy urine due     consume nutrients for energy, leading
           to excessive protein loss, weight gain from     to the production of by-products that
           fluid retention, high cholesterol levels, and   must be eliminated. In humans, organs



                                                    98               Student’s Book - Form Three



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     BIOLOGY FORM 3 FINAL EDITED 16.09.2025.indd   98
     BIOLOGY FORM 3 FINAL EDITED 16.09.2025.indd   98 KAMISHNA                            23/10/2025   11:52:45                     KAMISHNA
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